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Application of titanium in 3D printing medicine

Nov 25, 2021

Titanium and titanium alloy is a kind of excellent cost-effective pro-bio metallic metal, it has a good affinity and fusion with the human body, which has become an indispensable bio metallic material in the medical field. It is called bimetallic material, which is the material that implants it into an organism to repair organs and restore its function, Titanium and titanium alloy can be made into teeth and bones, or into soft tissue such as the heart valves, meninges, peritoneum, and so on. As we all know, the metal parts implanted in the body are always soaked in blood, lymphatic fluid, joint fluid, and other body fluids, so there must be a high degree of corrosion resistance and long-term stability, Metals must have no effect on human autonomic nerve and taste. Titanium and some titanium alloys are such materials, so they are called biophilic metals.

After 70 years of development and application, industrial pure titanium, Ti-6Al-4V, Ti-6Al-4VELI, and other titanium alloys have become excellent biophilic metal materials and have been widely used in the pharmaceutical industry at home and abroad, especially since the advent of 3D printing technology. Here is a brief introduction to 3D printing titanium alloy pharmaceutical products.

3D printing of human organs

● Skull

On August 28, 2014, when Hu, a 46-year-old farmer from Zhouzhi, Shaanxi Province, was building his own house, he fell from the third floor and hit a pile of wood. His left brain cap was smashed. After surgery in the local hospital, Hu's life was intact, but his left brain cap was sunken and became a "half head" in the eyes of others. In addition to looking different from ordinary people, the accident also injured Hu's vision and language function. In order to restore its image, the doctor used 3D printing technology to assist in the design of the shape of the defective skull, designed titanium mesh to reconstruct the defective Cranioorbital bone, made the defective left "brain cover", and finally realized left-right symmetry.

● spine

In August 2014, the research team of Peking University successfully implanted a 3D printed spine into a 12-year-old boy, which is the first in the world. It is understood that the little boy's spine grew a malignant tumor after a football injury, and the doctor had to choose to remove the spine where the tumor was located. However, the special thing about this operation is that the doctor did not use the traditional spine transplantation, but implanted a 3D printed titanium spine, which can be very well combined with the existing bones and shorten the patient's recovery time. Because the implanted 3D spine can be well combined with the surrounding bones, it does not need much "anchoring". In addition, the researchers also set up micropores on it to help the bone grow between the alloys. In other words, the implanted 3D printed spine will grow firmly with the original spine. This also means that there will be no loosening in the future.


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